教育经历：
2001-2004年：理学博士，微生物学专业，中国科学院微生物研究所
1998-2001年：理学硕士，微生物学专业，华中农业大学
1994-1998年：工学学士，农产品加工与储运专业，山东农业大学
工作经历：
2020.3至今： 研究员，河北大学
2016.10-2020.3：项目研究员，中国科学院微生物研究所
2008.12-2016.9：副研究员，中国科学院微生物研究所
2013.6-2014.6： 访问学者，美国威斯康辛大学-麦迪孙分校 （University of Wisconsin-Madison）
2012.3-2012.6： 访问学者，荷兰艺术和科学皇家学院真菌生物多样性中心（CBS-KNAW）
2010.6-2010.11：访问学者，荷兰艺术和科学皇家学院真菌生物多样性中心（CBS-KNAW）
2004.7-2008.11：助理研究员，中国科学院微生物研究所
奖励荣誉：
2009年获中国科学院“卢嘉锡青年人才奖”；
2012年“中国科学院青年创新促进会”会员；
2018年西藏自治区科学技术一等奖排名14/20；
社会服务工作：
国际真菌分类委员会异担子菌工作组委员
中国菌物学会工业与食品真菌专业委员会副主任委员
中国微生物学会真菌分会委员
《中国真菌学》编委
执教课程：课程名称（本科生/研究生）
本科生课程：系统生物学、生物信息技术科研实训
研究生课程：生命科学前沿研究进展、生物医药技术与研究进展
国际合作研究：
1. 国际合作：外担菌目系统发育、寄主专一性与进化研究
合作者：Prof. Dr. Dominik Begerow, Ruhr-University Nochum, Germany
2. 国际合作：BYE TOL: The Basidiomycetous YEasts Tree Of Life
合作者：Prof. Dr. Teun Boekhout, Westerdijk Fungal Biodiversity Institute, The Netherlands
【科研领域】
实验室研究方向和内容
酵母菌及相关丝状真菌系统学、进化基因组学及重要经济价值酵母菌应用开发研究。
1. 酵母菌生物多样性和生态学研究：对我国及世界酵母菌物种多样性和生态功能进行调查和研究，利用分子系统学、群体遗传学、系统基因组学和生态基因组学等方法，重建酵母菌及相关丝状真菌的演化历程和探讨单细胞和丝状类群间的演化关系，揭示生态、寄主和地理隔离等因素对其遗传分化与物种形成的作用。重点对特殊环境（低温、干燥、高辐射、高压）和重要生物基质（如地衣、重要植物、海洋生物）来源的酵母菌多样性和生态功能进行研究。
2. 酵母菌遗传和进化研究：利用基因编辑等遗传手段和比较基因组学、进化基因组学，探讨特殊生态、生理及代谢功能类群的环境适应机制、遗传特性和调控机制以及其基因组进化规律，从而阐明基因组进化和环境、寄主的进化关系。
3. 酵母菌新型表达系统研究：对具有各种抗逆性和特殊代谢途径等酵母菌进行系统筛选，选择具有外源蛋白表达系统开发潜力的类群进行遗传操作及代谢途径改造，研发高效可控的适用于不同需求外源基因表达系统。重点开展重要低温酶类和高价值重组疫苗的表达系统。
4. 酵母菌产业化开发：在拓展传统酵母菌（如酿酒酵母）在食品发酵等行业应用的基础上，重点开展非传统酵母菌在生物能源、生物医药和环境保护等行业中的产业化开发。
【代表性论文】
（*通讯作者，#共同第一作者）
1. Jiang YL, Bao WJ, Liu F, Wang GS, Yurkov A.M, Ma Q, Hu ZD, Chen XH, Zhao WN, Li AH, Wang QM*. 2024. Proposal of one new family, seven new genera and seventy new basidiomycetous yeast species mostly isolated from Tibet and Yunnan provinces, China. Studies in Mycology, 109: 57-153.
2. Liu MM, Zhu HH, Bai J, Tian ZY, Zhao YJ, Boekhout T, Wang QM*. 2024. Breast cancer colonization by Malassezia globosa accelerates tumor growth. mBio, e0199324. doi: 10.1128/mbio.01993-24.
3. Liu F, Hu ZD, Zhao XM, Zhao WN, Feng ZX, Yurkov A, Alwasel S, Boekhout T, Bensch K, Hui FL, Bai FY, Wang QM*. 2024. Phylogenomic analysis of the Candida auris-Candida haemuli clade and related taxa in the Metschnikowiaceae, and proposal of thirteen new genera, fifty-five new combinations and nine new species. Persoonia, 52: 22-43.
4. Liu F, Hu ZD, Yurkov A, Chen XH, Bao WJ, Ma Q, Zhao WN, Pan S, Zhao XM, Liu JH, Wang QM*, Boekhout T. 2024. Saccharomycetaceae: delineation of fungal genera based on phylogenomic analyses, genomic relatedness indices and genomics-based synapomorphies. Persoonia, 52: 1-21.
5. Liu M, Jiang YL, Zhang YX, Wang QM*. 2024. Nakazawaea tricholomae f.a., sp. nov., a novel ascomycetous yeast species isolated from two mushroom species in China. Curr Microbiol, 81(3): 78.
6. Liu M, Ding RX, Zhang YX, Li HZ, Wang QM*. 2024. Wickerhamomyces corioli f.a., sp. nov., a novel yeast species discovered in two mushroom species. Int J Syst Evol Microbiol, 74(4).
7. Wu F, Feng ZX, Wang MM, Wang QM*. 2023. Proposal of four new Aureobasidium species for exopolysaccharide production. J Fungi (Basel), 9(4): 447.
8. Liu F, Li YY, Li W, Wang QM*. 2023. The completed genome data of the pathogenic fungus Exobasidium cylindrosporum. Plant Dis, 107(1): 201-204.
9. Li YY, Liu F, Wang QM*. 2023. The first complete genome resource for the plant-pathogenic fungus Exobasidium rhododendri. Phytopathology, 113(6): 1133-1136.
10. Yu HT, Shang YJ, Zhu HY, Han PJ, Wang QM, Santos ARO, Barros KO, Souza GFL, Alvarenga FBM, Abegg MA, Rosa CA, Bai FY. 2023. Yueomyces silvicola sp. nov., a novel ascomycetous yeast species unable to utilize ammonium, glutamate, and glutamine as sole nitrogen sources. Yeast, 40(11): 540-549.
11. de Hoog S, Walsh TJ, Ahmed SA, Alastruey-Izquierdo A, Alexander BD, Arendrup MC, Babady E, Bai F-Y, Balada-Llasat J-M, Borman A, Chowdhary A, Clark A, Colgrove RC, Cornely OA, Dingle TC, Dufresne PJ, Fuller J, Gangneux J-P, Gibas C, Glasgow H, Gräser Y, Guillot J, Groll AH, Haase G, Hanson K, Harrington A, Hawksworth DL, Hayden RT, Hoenigl M, Hubka V, Johnson K, Kus JV, Li R, Meis JF, Lackner M, Lanternier F, Leal SM Jr, Lee F, Lockhart SR, Luethy P, Martin I, Kwon-Chung KJ, Meyer W, Nguyen MH, Ostrosky-Zeichner L, Palavecino E, Pancholi P, Pappas PG, Procop GW, Redhead SA, Rhoads DD, Riedel S, Stevens B, Sullivan KO, Vergidis P, Roilides E, Seyedmousavi A, Tao L, Vicente VA, Vitale RG, Wang QM, Wengenack NL, Westblade L, Wiederhold N, White L, Wojewoda CM, Zhang SX. 2023.A conceptual framework for nomenclatural stability and validity of medically important fungi: a proposed global consensus guideline for fungal name changes supported by ABP, ASM, CLSI, ECMM, ESCMID-EFISG, EUCAST-AFST, FDLC, IDSA, ISHAM, MMSA, and MSGERC. J Clin Microbiol, 61(11): e0087323.
12. Peris D, Ubbelohde EJ, Kuang MC, Kominek J, Langdon QK, Adams M, Koshalek JA, Hulfachor AB, Opulente DA, Hall DJ, Hyma K, Fay JC, Leducq JB, Charron G, Landry CR, Libkind D, Gonçalves C, Gonçalves P, Sampaio JP, Wang QM, Bai FY, Wrobel RL, Hittinger CT. 2023. Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces. Nat Commun ,14(1): 690.
13. Steins L, Guerreiro MA, Duhamel M, Liu F, Wang QM, Boekhout T, Begerow D. 2023. Comparative genomics of smut fungi suggest the ability of meiosis and mating in asexual species of the genus Pseudozyma (Ustilaginales). BMC Genomics, 24(1): 321.
14. Witfeld F, Guerreiro M.A, Nitsche F, Wang QM, Nguyen Hai DT. Begerow D. Peribolosporomycetes class. nov.: description of a new heat resistant and osmotolerant basidiomycete lineage, represented by Peribolospora gen. nov., P. kevripleyi sp. nov., and P. baueri sp. nov. Mycol Progress, 22: 30.
15. Zhang BQ, Li XG, Li GJ, Wang QM*, Wang MM*. 2022. Cadophora species from marine glaciers in the Qinghai-Tibet Plateau: an example of unsuspected hidden biodiversity. IMA Fungus, 13(1): 15.
16. Li YY, Wang MM, Groenewald M, Li AH, Guo YT, Wu F, Zhang BQ, Tanaka E, Wang QM*, Bai FY, Begerow D. 2022. Proposal of two new combinations, twenty new species, four new genera, one new family, and one new order for the anamorphic basidiomycetous yeast species in Ustilaginomycotina. Front Microbiol, 12: 777338.
17. Bai FY, Han DY, Duan SF, Wang QM. 2022. The Ecology and Evolution of the Baker's Yeast Saccharomyces cerevisiae. Genes, 13(2): 230.
18. He PY, Shao XQ, Duan SF, Han DY, Li K, Shi JY, Zhang RP, Han PJ, Wang QM, Bai FY. 2022. Highly diverged lineages of Saccharomyces paradoxus in temperate to subtropical climate zones in China. Yeast, 39(1-2): 69-82.
19. Song L, Shi JY, Duan SF, Han DY, Li K, Zhang RP, He PY, Han PJ, Wang QM, Bai FY. 2021. Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature. Genome Res, 31(4): 622-634.
20. Wang MM, Groenewald M, Wu F, Guo YT, Wang QM*, Boekhout T. 2021. Intraspecific nucleotide divergence in Saccharomycodes ludwigii, and proposal of Saccharomycodes pseudoludwigii sp. nov, a new apiculate yeast isolated from China. Antonie Van Leeuwenhoek, 114(5): 553-559.
21. Liu Z, Wang MM, Wang GS, Li AH, Wangmu, Wang QM*. 2019. Hanseniaspora terricola sp. nov., an ascomycetous yeast isolated from Tibet. Int J Syst Evol Microbiol, 71(3).
22. Wang GS, Sun Y, Wang M, Wang QM*. 2021. Colacogloea armeniacae sp. nov., a novel pucciniomycetous yeast species isolated from apricots. Mycoscience, 62(1): 42-46.
23. Yurkov A, Alves A, Bai FY, Boundy-Mills K, Buzzini P, Čadež N, Cardinali G, Casaregola S, Chaturvedi V, Collin V, Fell JW, Girard V, Groenewald M, Hagen F, Hittinger CT, Kachalkin AV, Kostrzewa M, Kouvelis V, Libkind D, Liu XZ, Maier T, Meyer W, Péter G, Piątek M, Robert V, Rosa CA, Sampaio JP, Sipiczki M, Stadler M, Sugita T, Sugiyama J, Takagi H, Takashima M, Turchetti B, Wang QM, Boekhout T. 2021. Nomenclatural issues concerning cultured yeasts and other fungi: why it is important to avoid unneeded name changes. IMA Fungus, 12(1): 18.
24. Boekhout T, Amend A.S, El Baidouri F, Gabaldon T, Geml J, Mittelbach M, Robert V, Tan C.S, Turchetti B, Vu D, Wang QM, Yurkov A. 2021. Trends in yeast diversity discovery. Fungal Diversity, 114, 491-537.
25. 赵伟娜, 张冰, 王启明*. 2021. 耳念珠菌致病及耐药机制的研究进展. 中国科学:生命科学, 51(09): 1254-1263.
26. Wang GS, Zhou Y, Xue L, Li AH, Wangmu, Wang QM*. 2020. Teunia rosae sp. nov. and Teunia rudbeckiae sp. nov. (Cryptococcaceae, Tremellales), two novel basidiomycetous yeast species isolated from flowers. Int J Syst Evol Microbiol, 70(10): 5394-5400.
27. Sun Y, Wang GS, Li AH, Wangmu, Chui XQ, Jiang JH, Wang QM*. 2020. Phaeotremella camelliae sp. nov. (Phaeotremellaceae, Tremellales), A Novel Yeasts Isolated from Tea-Oil Fruits in Jiangxi Province, China. Curr Microbiol, (10): 3168-3173.
28. Li AH, Yuan FX, Groenewald M, Bensch K, Yurkov AM, Li K, Han PJ, Guo LD, Aime MC, Sampaio JP, Jindamorakot S, Turchetti B, Inacio J, Fungsin B, Wang QM*, Bai FY*. 2020. Diversity and phylogeny of basidiomycetous yeasts from plant leaves and soil: Proposal of two new orders, three new families, eight new genera and one hundred and seven new species. Stud Mycol, 96: 17-140.
29. Duan SF, Han PJ, Wang QM, Liu WQ, Shi JY, Li K, Zhang XL, Bai FY. 2018. The origin and adaptive evolution of domesticated populations of yeast from Far East Asia. Nat Commun 9: 690.
30. S-F Duan, J-Y Shi, Q Yin, R-P Zhang, P-J Han, Q-M Wang, F-Y Bai. 2019. Reverse Evolution of a Classic Gene Network in Yeast Offers a Competitive Advantage. Curr Biol 29(7):1126-1136.e5
31. Peris D, Moriarty RV, Alexander WG, Baker E, Sylvester K, Sardi M, Langdon QK, Libkind D, Wang QM, Bai FY, Leducq JB, Charron G, Landry CR, Sampaio JP, Gonçalves P, Hyma KE, Fay JC, Sato TK, Hittinger CT. 2017. Hybridization and adaptive evolution of diverse Saccharomyces species for cellulosic biofuel production. Biotechnol Biofuels eCollection 2017.
32. Alimadadi N, Soudi MR, Wang SA, Wang QM, Talebpour Z, Bai FY. Starmerella orientalis f.a., sp. nov., an ascomycetous yeast species isolated from flowers. Int J Syst Evol Microbiol 66: 1476-1481.
33. Han PJ, Li AH, Wang QM*, Bai FY. 2016. Ballistosporomyces changbaiensis sp. nov. and Ballistosporomyces bomiensis sp. nov., two novel species isolated from shrubs plant leaves. Antonie van Leeuwenhoek 109: 965-970.
34. Wang QM, Groenewald M, Takashima T, Theelen B, Han PJ, Liu XZ, Boekhout T, Bai FY. 2015. Phylogeny of yeasts and related filamentous fungi within Pucciniomycotina determined from multigene sequence analyses. Stud Mycol 81: 27-54.
35. Liu XZ#, Wang QM#, Theelen B, Groenewald M, Bai FY, Boekhout T. Phylogeny of tremellomycetous yeasts and related dimorphic and filamentous basidiomycetes reconstructed from multiple gene sequence analyses. Stud Mycol 81: 1-26
36. Wang QM, Begerow D, Groenewald M, Liu XZ, Theelen B, Bai FY, Boekhout T. 2015. Multigene phylogeny and taxonomic revision of yeasts and related fungi in the Ustilaginomycotina. Stud Mycol 81: 55-84
37. Wang QM, Groenewald M, Göker M, Lumbsch HT, Leavitt SD, Yurkov AM, Theelen B, Liu XZ, Bai FY, Boekhout T. Phylogenetic classification of yeasts and related taxa within Pucciniomycotina. Stud Mycol 81: 149-189
38. Liu XZ, Wang QM, Göker M, Groenewald M, Kachalkin AV, Lumbsch HT, Millanes AM, Wedin M, Yurkov AM, Boekhout T, Bai FY. 2015. Towards an integrated phylogenetic classification of the Tremellomycetes. Stud Mycol 81: 85-147
39. Wang QM, Theelen B, Groenewald M, Bai FY, Boekhout T. 2014. Moniliellomycetes and Malasseziomycetes,two new classes in Ustilaginomycotina. Persoonia 33: 4147.
40. Wang QM, Liu WQ, Gianni L, Wang, SA & Bai, FY. 2012. Surprisingly diverged populations of Saccharomyces cerevisiae in natural environments remote from human activity. Molecular Ecology 21: 5404-5417.
41. Wang QM, Zhang YH, Wang B & Wang L. 2016. Talaromyces neofusisporus and T. qii, two new species of section Talaromyces isolated from plant leaves in Tibet, China. Scientific Reports 6: 18622.
42. Wang L, Wang QM*. 2015. Molecular phylogenetic analysis of ballistoconidium-forming yeasts in Trichosporonales (Tremellomycetes): A proposal for Takashimella gen. nov. and Cryptotrichosporon tibetense sp. nov. PLoS ONE 10: e0132653.
43. Wang L, Groenewald M, Wang QM*, Boekhout T. 2015. Reclassification of Saccharomycodes sinensis, proposal of Yueomyces sinensis gen. nov., comb. nov. within Saccharomycetaceae (Saccharomycetales, Saccharomycotina). PLoS ONE 10: e0136987.
44. Bing J, Han PJ, Liu WQ, Wang QM, Bai FY. 2014. Evidence for a Far East Asian origin of lager beer yeast. Current Biology 24: R380-R381.
45. Sylvester K, Wang QM, James B, et al. 2015. Temperature and host preferences drive the diversification of Saccharomyces and other yeasts: a survey and the discovery of eight new yeast species. FEMS Yeast Research doi: 10.1093/femsyr/fov002.
46. Schoch CL, Seifert KA, Huhndorf S, Seifert KA, Huhndorf S, Robert V, Spouge JL, Levesque CA, Chen W, ……,Wang QM et al. 2012. Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi. Proceedings of the National Academy of Sciences of the United States of America 109: 6241-6246.
47. Liu WQ, Han PJ, Qiu JZ & Wang QM*. 2012. Naumovozyma baii sp. nov., an ascomycetous yeast species isolated from rotten wood in a tropic forest. Int J Syst Evol Microbiol 62: 3096-3099.
48. Han PJ, Qiu JZ & Wang QM*, Bai FY. 2012. Udeniomyces kanasensis sp. nov., a ballistoconidium-forming yeast species in the Cystofilobasidiales. Antonie van Leeuwenhoek 102: 45-51.
49. Chen R, Jiang YM, Wei SC & Wang QM. 2012. Kwoniella shandongensis sp. nov., a novel basidiomycetous yeast species from apple orchard. Int J Syst Evol Microbiol 62: 2774-2777.
50. Wang QM, Boekhout T & Bai FY. 2012. Bensingtonia rectispora sp. nov. and Bensingtonia bomiensis sp. nov., novel ballistoconidium-forming yeast species from plant leaves collected in Tibet. Int J Syst Evol Microbiol 62: 2039-44.
51. Liu XZ, Wang QM, Boekhout T & Bai FY. 2012. Derxomyces amylogenes sp. nov., Derxomyces bambusicola sp. nov. and Derxomyces corylopsis sp. nov., three novel ballistoconidium-forming yeast species isolated from subtropical plant leaves. Int J Syst Evol Microbiol 62:996-1001.
52. Wang QM*, Boekhout T & Bai FY. 2011. Cryptococcus foliicola sp. nov. and Cryptococcus taibaiensis sp. nov., novel basidiomycetous yeast species from plant leaves. J Gen Appl Microbiol 57: 285-291.
53. Wang QM, Bai FY, Fungsin B, Boekhout T & Nakase T. 2010. Proposal of Mingxiaea gen. nov. for the anamorphic basidiomycetous yeast species in the Bulleribasidium clade (Tremellales) based on molecular phylogenetic analysis and description of four novel Mingxiaea species. Int J Syst Evol Microbiol 60: 210-219.
54. Chen R, Wei SC, Jiang YM, Wang QM & Bai FY. 2010. Kazachstania taianensis sp. nov., a novel ascomycetous yeast species from orchard soil. Int J Syst Evol Microbiol 60: 1473-1476.
55. Wang QM, Xu J, Wang H, Li J & Bai FY. 2009. Torulaspora quercuum sp. nov. and Candida pseudohumilis sp. nov., novel yeasts from human and forest habitats. FEMS Yeast Res 9: 1322-1326.
56. Wang C, Wang QM, Jia JH & Bai FY. 2009. Candida pseudocylindracea sp. nov. and Candida wuzhishanensis sp. nov. from Hainan Island, southern China. Mycosystema 28: 79-85.
57. Wang QM & Bai FY. 2008. Molecular phylogeny of basidiomycetous yeasts in the Cryptococcus luteolus lineage (Tremellales) based on nuclear rRNA and mitochondrial cytochrome b gene sequence analyses: proposal of Derxomyces gen. nov. and Hannaella gen. nov., and description of eight novel Derxomyces species. FEMS Yeast Research 8: 799-814.
58. Wang QM, Li J, Wang SA & Bai FY. 2008. Rapid Differentiation of Phenotypically Similar Yeast Species by Single-Strand Conformation Polymorphism Analysis of Ribosomal DNA. Applied and Environmental Microbiology 74: 2604-2611.
59. Wang QM, Jia JH & Bai FY. 2008. Diversity of basidiomycetous phylloplane yeasts belonging to the genus Dioszegia (Tremellales) and description of Dioszegia athyrium sp. nov., Dioszegia cream sp. nov and Dioszegia xingshanensis sp. nov. Antonie van Leeuwenhoek 93: 391-399.
60. Wang QM, Wang SA, Jia JH & Bai FY. 2007. Cryptococcus tibetensis sp. nov., a novel basidiomycetous anamorphic yeast species isolated from plant leaves. J Gen Appl Microbiol 53: 281-285.
61. Wang QM, Jia JH & Bai FY. 2006. Pseudozyma hubeiensis sp. nov. and Pseudozyma shanxiensis sp. nov., novel ustilaginomycetous anamorphic yeast species from plant leaves. Int J Syst Evol Microbiol 56: 289-293.
62. Wang QM, Jia JH & Bai FY. 2006. Bensingtonia pseudonaganoensis sp. nov., a novel ballistoconidium-forming yeast species isolated from plant leaves. Antonie van Leeuwenhoek 89: 261-266.
63. Wang QM, Bai FY, Lu HZ, Jia JH & M Takashima. 2004. Bullera cylindrica, Bullera hubeiensis and Bullera nakasei, novel ballistoconidium-forming yeast species isolated from plant leaves. Int J Syst Evol Microbiol 54: 1877-1822.
64. Wang QM & Bai FY. 2004. Four new yeast species of the genus Sporobolomyces from plant leaves. FEMS Yeast Research 4: 579-586.
65. Wang QM, Bai FY, Zhao JH & Jia JH. 2003. Bensingtonia changbaiensis sp. nov. and Bensingtonia sorbi sp. nov., novel ballistoconidium- forming yeast species isolated from plant leaves. Int J Syst Evol Microbiol 53: 2085-2089.
66. Wang QM, Bai FY, Zhao JH & Jia JH. 2003. Dioszegia changbaiensis sp. nov., a basidiomycetous yeast species isolated from northeast China. J Gen Appl Microbiol 49: 295-299.
67. ML Xue, LQ Zhang, QM Wang, JS Zhang & FY Bai. 2006. Metschnikowia sinensis sp. nov., Metschnikowia zizyphicola sp. nov. and Metschnikowia shanxiensis sp. nov., three novel yeast species from jujube fruit. Int J Syst Evol Microbiol 56: 2245-2250.
68. Lu HZ, Jia JH, Wang QM & Bai FY. 2004. Candida asparagi sp. nov., Candida diospyri sp. nov. and Candida qinlingensis sp. nov., novel anamorphic ascomycetous yeast species. Int J Syst Evol Microbiol 54: 1409-1414.
69. Bai FY, Cai Y, Wang QM & Ohkubo H. 2004. Rhodotorula oryzae sp. nov., a novel basidiomycetous yeast species isolated from paddy rice. Antonie van Leeuwenhoek 86: 295-299.
70. Zhao JH, Bai FY, Wang QM & Jia JH. 2003. Sporobolomyces bannaensis, a new ballistoconidium-forming yeast species in the Sporidiobolus lineage. Int J Syst Evol Microbiol 53: 2091-2093.
